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Millions of men all over the world suffer from erectile dysfunction - difficulty in achieving or maintaining penis erections. 

 

For some, the erection problems are partial or occasional. For others, there may be total impotence - the inability at all times to achieve penis erections adequate for sexual intercourse.

 

  • Over half of all men over age 40 experience some changes in their erectile function. 

  • At age 70, two-thirds of all men have reduced erectile function.

 

 

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In the past, such sexual dysfunction was treated with injections, surgery, and other procedures, which can be painful and embarrassing and, worst of all, are of uncertain success. Today, there are much better and more certain options that help men with erection difficulties. 

 

Erectile Dysfunction Treatment: Viagra, Levitra and Cialis

 

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Until the late 1990s, there were no truly effective oral medications for erectile dysfunction — the inability to achieve or sustain an adequate erection for sexual activity. The useful drugs that were available had to be injected into the penis or inserted into the urethra.

Treatment of erectile dysfunction is much easier now, thanks to a class of drugs called phosphodiesterase-5 (PDE-5) inhibitors. The medications — sildenafil (Viagra), vardenafil (Levitra) and tadalafil (Cialis) — all improve erectile function in the same basic way, but they differ in how quickly they take effect and how long their effects last.

 

Viagra, Levitra and Cialis: How they work

Viagra, Levitra and Cialis prevent the breakdown of nitric oxide, a chemical messenger that promotes relaxation and opening of the blood vessels that supply erectile tissue in the penis. Under the influence of nitric oxide, these vessels expand and stay dilated. Increased blood flow makes erectile tissue swell and compress the veins that carry blood out of the penis, resulting in a full erection.

PDE-5 inhibitors do not automatically trigger erections. Sexual stimulation is needed to start the whole process. The medications enable a more complete response to sexual stimulation.

Many clinical trials have shown that PDE-5 inhibitors improve erectile function regardless of the underlying cause or causes. Viagra, Levitra and Cialis increase the number and quality of erections and sexual experiences in men with erectile dysfunction due to arteriosclerosis, diabetes, spinal cord injury, depression or the aftereffects of prostate cancer surgery.

 

Similarities and differences

The drugs have slightly different chemical compositions that affect how quickly they work and wear off. Other distinctions — for example, which drug may be best for men of different ages or with different medical conditions — aren't known. No study has directly compared these three medications.

  Viagra (sildenafil) Levitra (vardenafil) Cialis (tadalafil)
Usual Doses 50 mg per day 10 mg per day 10 mg per day
Maximum Doses 100 mg per day 20 mg per day 20 mg per day
Available As 20mg, 25mg, 50mg, 100mg tablets 2.5mg, 5mg, 10mg, 20mg tablets 5mg, 10mg, 20mg tablets
How to Take Without Food Without Food With or Without Food
When to Take 30 to 60 minutes before sexual activity 30 to 60 minutes before sexual activity 30 minutes before sexual activity
Duration of Effects Up to 4 hours Up to 4 hours 24 to 36 hours
How Often to Use Up to once a day Up to once a day Up to once a day
Possible Side Effects Headache, flushing, indigestion, stuffy or runny nose, upset stomach, diarrhea Headache, flushing, indigestion, stuffy or runny nose, upset stomach, dizziness Headache, indigestion, back pain, muscle aches, flushing, stuffy or runny nose
Warnings Do not take with nitrates (Nitro-Dur, others), or if you have certain heart valve problems. Should be used with caution or not used at all with alpha blockers. Should not be used with some antibiotic, antiviral or antifungal medications. Do not take with nitrates (Nitro-Dur, others) or alpha blockers (Hytrin, Cardura, others), or if you have certain heart valve problems. Should be used with caution or not used at all with alpha blockers. Should not be used with some antibiotic, antiviral or antifungal medications. Do not take with nitrates (Nitro-Dur, others) or alpha blockers (Hytrin, Cardura, others), or if you have certain heart valve problems. Should be used with caution or not used at all with alpha blockers. Should not be used with some antibiotic, antiviral or antifungal medications.

 

Several factors may affect your choice of medication, including how well your body responds to one drug over another and how long you want the effects of each dose to last.

 

Not Safe for Everyone

Although these medications can help many people, not all men can safely take them. PDE-5 inhibitors may worsen certain medical conditions and interact with a number of drugs. Erectile dysfunction medications are dangerous when used with nitrate medications, such as nitroglycerin (Nitro-Dur, others), often prescribed to prevent or treat acute angina (chest pain due to coronary artery disease). Both types of medication dilate blood vessels, and their combined effects can cause dizziness, low blood pressure and loss of consciousness.

In rare cases, men using PDE-5 inhibitors have suffered permanent, total vision loss due to nonarteritic anterior ischemic optic neuropathy (NAION). Because NAION and erectile dysfunction share many of the same risk factors, it's unclear whether the drug or an underlying condition is responsible. If you're considering an erectile dysfunction drug but have a retinal disorder, such as diabetic retinopathy, see your eye doctor first.

 

Realistic Expectations

Occasional erectile dysfunction is a common problem, particularly as men age. Medication won't make you feel like you're 20 again, but it can help you achieve satisfying sexual relations more often.

 

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This is a prescription drug used to treat male penis erection difficulties, or erectile dysfunction (ED). 

 

  • Since it first became available in 1998, this drug has helped about 16 million men around the world improve their sex lives.

  • The medicine works by increasing blood flow to the penis during sexual stimulation. It does not cause erections directly, but enhances the response to sexual stimulation.

  • It is not a hormone or an aphrodisiac. 

  • Once you take it, the drug can work in as quickly as 30 minutes and it works for 4 hours. For most patients, the medication can be taken as often as once a day.

  • A medical prescription is required for the purchase of this FDA approved drug. 

 

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This is one of the newest FDA approved, prescription drugs for solving penis erection difficulties (erectile dysfunction). 

 

According to a recent news release by Bayer/GlaxoSmithKline, ninety percent (90%) of men with erectile dysfunction reported improved erections with the use of Levitra. 

 

  • Each pill may work in as quickly as 25 minutes and may work for up to 24 hours.

  • This drug acts in the same way as Viagra (but is effective for longer periods), by blocking an enzyme called phosphodiesterase-5, or PDE-5. This helps the smooth muscles in the penis to relax, to increase blood flow and thus allow the penis to become and stay harder longer, to maintain an erection satisfactory for sexual intercourse.

  • The product does not cause erections directly but affects the response to sexual stimulation. It is not an aphrodisiac or a hormone.

  • The product has been clinically shown to improve erectile function even in men who had other health factors, like diabetes or prostate surgery.

  • Men using this medication reported having harder erections and improved overall sexual experiences.

  • A medical prescription is required for the purchase of this FDA approved drug. 

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This is a FDA approved prescription drug used to treat the physical problem of erectile dysfunction in men. 

 

  • The active ingredient in these tablets, tadalafil, belongs to a group of medicines called phosphodiesterase type 5 inhibitors. 

  • Following sexual stimulation, the drug works by helping the blood vessels in your penis to relax, allowing the flow of blood into your penis. The result is improved male erections. It can help a majority of men, with penis erection difficulties, to get and keep an erection when sexually aroused. 

  • The product does not cause erections directly but affects the response to sexual stimulation. It is not an aphrodisiac or a hormone.

  • According to clinical studies' data on this medication (tadalafil), men with ED reported a statistically significant improvement in successful sexual intercourse at 36 hours after taking the drug, compared to placebo. In Europe, where it was first launched in 2003 Cialis has been dubbed the "weekend erections pill".

  • This product is allowing men to choose the moments when they want to have intimacy. In all studies, compared with placebo, use of this medication demonstrated consistent and statistically significant improvement and the treatment effect did not diminish over time. 

  • Other new findings - including a summary of cardiovascular safety data - showed no increased incidence of cardiovascular events during clinical studies.

  • A medical prescription is required for the purchase of this FDA approved medication. 

 

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